超级宝妈|《柳叶刀》子刊：做好这件事，大大降低娃的哮喘风险( 三 ) 规范使用抗生

具体说来，就包括做好手卫生和家庭重要物品表面——桌子、衣物、餐具、毛巾、洗手台、家具等的消毒，这可以大大减轻细菌聚集和细菌感染的风险。
所以，在一天中你家娃会洗几次手？

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参考文献：
1.Patrick DM, Sbihi H, Dai DLY, Al Mamun A, Rasali D, Rose C, Marra F, Boutin RCT, Petersen
C, Stiemsma LT et al: Decreasing antibiotic use, the gut microbiota, and asthma incidence in
children: evidence from population-based and prospective cohort studies. The Lancet Respiratory Medicine, 2020.
2. Abreo A, Gebretsadik T, Stone CA, Hartert TV. The impact of modifiable risk factor reduction on childhood asthma development. Clin Transl Med 2018; 7: 15.
3. Russell SL, Gold MJ, Hartmann M, et al. Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. EMBO Rep 2012; 13: 440–47.
4. Sokol H, Pigneur B, Watterlot L, et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl 5. Acad Sci USA 2008; 105: 16731–36.
5. Wang Q, Li F, Liang B, et al. A metagenome-wide association study ofgut microbiota in asthma in UK adults. BMC Microbiol 2018; 18: 114.
6. Fujimura KE, Sitarik AR, Havstad S, et al. Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation. Nat Med 2016; 22: 1187–91.
7. Wrigley DM. Inhibition of Clostridium perfringens sporulation by Bacteroides fragilis and short-chain fatty acids. Anaerobe 2004; 10: 295–300.
8. Ruiz VE, Battaglia T, Kurtz ZD, et al. A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity. Nat Commun 2017; 8: 518.
9. Maillard J-Y, Bloomfield S, Courvalin P, Essack S, Gandra S, Gerba C, Rubino J, Scott E:
Reducing antibiotic prescribing and addressing the global problem of antibiotic resistance by targeted hygiene in the home and everyday life settings: A Position Paper. American Journal of Infection Control 2020.
本文来源：医学界儿科频道
本文作者：蓝鲸晓虎